HRD testing
made easy
Use the trusted HRD genetic test that is accurate, easy-to-implement and cost-effective
HRD testing
made easy
Use the trusted HRD genetic test that is accurate,
easy-to-implement
and cost-effective
SeqOne presented his HRD scoring at the ESMO Gynaecological Cancers 2023 conference.
Learn more about HRD testing and Seqone’s HRD test: watch full GenomeWeb webinar replay
Download white paper
Understand how SeqOne provides high quality HRD genetic tests with fast turnaround time and lower cost.
Download our white paper “How to perform fast and accurate HRD testing while mitigating costs: a clinically validated and easy-to-implement HRD scoring using targeted panel and shallow whole genome“.
Download white paper
Understand how SeqOne provides high quality HRD genetic tests with fast turnaround time and lower cost.
Cost-effective
Our innovative approach makes it possible to implement a state-of-the-art HRD test easily and cost-effectively while delivering excellent results on both Illumina NextSeq and NovaSeq sequencers.
Accurate
Our HRD test has high correlation with clinical outcomes and results delivered using the reference test while requiring less genetic material and delivering fewer inconclusive results.
Efficient
Get efficient results even with samples of average quality. Our HRD test provides accurate results with 50ng of material and >20% cellularity to deliver better results more often.
Certified solution
SeqOne’s HRD test is clinically certified on the reference PAOLA-1 cohort and available on our CE-IVD(R) certified(1) genomic testing platform. (1) CE-IVDR certification expected in the first half of 2023.
Learn more about HRD Testing and SeqOne difference
Want to learn about state-of-the-art knowledge about HRD and how SeqOne is improving HRD test for ovarian cancer (less non-conclusive results, less genetic material needed, cost mitigation and technology agnostic)?
- HRD to predict sensitivity to PARPi maintenance therapy.
- How to measure HRD
- HRR gene panels to measure HRD
- Algorithmic tools and AI to predict HRD
- SeqOne’s improvements
Clear, understandable HRD reports
The SeqOne HRD test report provides:
- A clear positive/negative rating for each sample,
- A quantitative score that provides more visibility on the reasoning behind reported HRD status,
- A patent-pending HRD score calculation based on the following features contributing to the HRD test: Genomic instability, including Large Genomic Alteration (LGA), and a loss of Parental Copy (LPC) score, CCNE1 Copy Number Variations, Single Nucleotide Variants consisting of BRCA1/BRCA2 pathogenic variants and pathogenic variants in other genes.
Download example reports :
10 reasons to prefer SeqOne
1
From sequencer to final report
A true end-to-end solution for efficiency and traceability from raw data to easily understandable and actionable clinical report.
2
Supports both somatic and constitutional analysis
SeqOne supports both somatic and constitutional analysis on a unified platform.
3
Machine-Learning driven variant classification
Biological and clinical pre-classification based on European International Guidelines (ACMG, AMP, ComPerMed) and on machine learning systems.
4
Find all relevant mutations
SeqOne’s platform offers advanced bioinformatics that detect complex variants and support all the important usages including UMIs for liquid biopsy analysis, noise and artefact reduction for a lower false positive rate.
5
Easy-to-use interpretation environment
An intuitive visual environment providing tools to boost interpretation efficiency. SeqOne’s platform offers specific applications to address the requirements of each genomic test.
6
Quality Control
QC base-per-base coverage ensuring true negative assertion.
7
World-class support in less than 1 business day
Get the help you need to deliver the best results.
8
Certification
A platform built for clinical diagnostic routine: CE-IVD, HDS and ISO27001 certified.
9
Data security
SeqOne stores data on an ISO27001 compliant platform and offers additional user-specific data encryption to ensure data stays safe.
10
Up-to-date knowledge
Regularly updated molecular and clinical knowledge bases (biological, clinical and therapeutic) with update notification to enable retrospective analysis of variants, treatments and clinical trials.
10 reasons to prefer SeqOne
1
From sequencer to final report
A true end-to-end solution for efficiency and traceability from raw data to easily understandable and actionable clinical report.
2
Supports both somatic and constitutional analysis
SeqOne supports both somatic and constitutional analysis on a unified platform.
3
Machine-Learning driven variant classification
Biological and clinical pre-classification based on European International Guidelines (ACMG, AMP, ComPerMed) and on machine learning systems.
4
Find all relevant mutations
SeqOne’s platform offers advanced bioinformatics that detect complex variants and support all the important usages including UMIs for liquid biopsy analysis, noise and artefact reduction for a lower false positive rate.
5
Easy-to-use interpretation environment
An intuitive visual environment providing tools to boost interpretation efficiency. SeqOne’s platform offers specific applications to address the requirements of each genomic test.
6
Quality Control
QC base-per-base coverage ensuring true negative assertion.
7
World-class support in less than 1 business day
Get the help you need to deliver the best results.
8
Certification
A platform built for clinical diagnostic routine: CE-IVD, HDS and ISO27001 certified.
9
Data security
SeqOne stores data on an ISO27001 compliant platform and offers additional user-specific data encryption to ensure data stays safe.
10
Up-to-date knowledge
Regularly updated molecular and clinical knowledge bases (biological, clinical and therapeutic) with update notification to enable retrospective analysis of variants, treatments and clinical trials.
Trusted by major European labs
SeqOne Genomics is trusted by major European laboratories for their routine testing.
About SeqOne
The vision uniting the SeqOne team is a desire to improve patient outcomes through better genomic analysis. We invest significantly on research and development to ensure that our platform offers the most effective, easy-to-use solutions in oncology and inherited diseases.
This ambitious program is driven by a team of experts covering all aspects of medical genomics; from clinicians, bioinformaticians, biologists and information technology specialists to experts in algorithmics, artificial intelligence, security and big data.
Download white paper
Understand how SeqOne provides high quality HRD genetic tests with fast turnaround time and lower cost.
Download our white paper “How to perform fast and accurate HRD testing while mitigating costs: a clinically validated and easy-to-implement HRD scoring using targeted panel and shallow whole genome“.
