Somatic
Germline

Advancing Precision Oncology
with AI-Powered Bioinformatics.

Optimize NGS data analysis. Reduce turnaround times.

Confidently deliver personalized treatment insights.

Comprehensive somatic detection with advanced oncology signatures

Leverage premium annotation databases for superior variant interpretation

Adjust panels on-the-fly to meet evolving clinical needs

Generate comprehensive clinical reports with all the insights you need at a glance

Molecular labs work tirelessly to decode the genetic complexities of cancer, turning NGS data into insights that guide patient care. Their expertise is essential and often time-sensitive.

SeqOne’s AI-powered bioinformatics suite is designed to support their work, helping streamline analysis and accelerate the path to precision oncology.

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Comprehensive analysis in one platform.

Secondary

Supported providers

Tertiary

Sample types

Quality

Power every analysis.

Discover our suite of Oncology applications.

SomaVar

Advanced Bioinformatics for Somatic DNA Panel Analysis from FASTQ files.

Variant Calling

SNVs, CNVs, SVs, InDels

Biomarkers & Signatures

MSI

Instrument Compatibility

Illumina, MGI, Element Biosciences

Wetlab Compatibility

Universal

Reference Genomes

Hg19 & Hg38

SomaCGP

SomaCGP supports NGS analysis of Comprehensive Genomic Profiling (CGP) from FASTQ files.

Variant Calling

SNVs, CNVs, SVs, InDels, exon skipping, DNA and RNA fusions

Biomarkers & Signatures

TMB, MSI, HRD

Instrument Compatibility

Illumina, MGI, Element Biosciences

Wetlab Compatibility

Universal

Reference Genomes

Hg19 & Hg38

SomaHRD

SomaHRD provides Homologous Recombination Defect score from shallow WGS

Variant Calling

Interoperable with SomaVar and SomaCGP

Signature

Genomic Instabiity score

Instrument Compatibility

Illumina, MGI, Element Biosciences

Wetlab Compatibility

Universal

Reference Genome

Hg19

SomaVar Tertiary

SomaVar tertiary supports annotation of variants from VCF files

Variant Calling

SNPs, InDels, CNVs, fusions

Wetlab Compatibility

AmoyDx, Pillar, ThermoFisher

SomaRNA

Supports RNA-seq data from targeted approaches to identify and view gene fusion events

Variant Calling

SomaVar pipeline

Biomarkers & Signatures

Fusions, exon skipping

Instrument Compatibility

Illumina, MGI, Element Biosciences

Wetlab Compatibility

Universal, capture or amplicon technology

Reference Genome

Hg19

SomaVar LF

SomaLF provides analytical capabilities for low fraction somatic variant analysis from liquid biopsy

Variant Calling

SNVs, InDels, structural variants

Quality Control

UMI technology to detect variants from 0.1% VaF

Instrument Compatibility

Illumina, MGI, Element Biosciences

Wetlab Compatibility

Universal

Reference Genomes

Hg19 & Hg38

SomaHemato

SomaHemato supports analysis of hematological cancer DNA panels from FASTQ files.

Variant Calling

FLT3-ID, KMT2A-PTD, Gene fusions

Biomarkers & Signatures

IGHV mutational status for CLL, TP53

Instrument Compatibility

Illumina, MGI, Element Biosciences

Wetlab Compatibility

Universal

Reference Genomes

Hg19 & Hg38

Redefining HRD Testing in Ovarian Cancer

Homologous Recombination Deficiency (HRD) is a key biomarker for guiding PARP inhibitor therapy in ovarian and other cancers. But traditional HRD testing can be slow and unreliable, leading to delayed or inconclusive results when treatment decisions matter most. SomaHRD changes that.

Built for molecular labs, SomaHRD delivers rapid, high-confidence HRD results, ensuring oncologists get timely, actionable insights to personalize patient care.

Why Labs Choose SomaHRD

  • 95% concordance with the PAOLA-1 Phase 3 clinical trial reference test
  • Reliable results with tumor content as low as 20%
  • Advanced genomic instability analysis integrating LGA, LPC, and BRCA1/2 assessment

See the Data Behind SomaHRD.

Download our White Paper for clinical validation details.

Case study

North West GLH’s journey to faster,
more reliable HRD testing

One of the UK’s leading genomic labs, North West Genomic Laboratory Hub, revolutionized its HRD testing workflow with SeqOne—reducing turnaround time, improving accuracy, and optimizing resource allocation.

The result?

Faster, more reliable insights for guiding precision oncology treatments.

The big advantage of using SeqOne for us is how transparent the process is: we can get high-resolution information on each sample and understand in detail how the genomic instability score is calculated. This gives us additional confidence when reporting clinical results to the doctors and patients we serve.

Read the full story

More than a platform

Your lab, our commitment.

Built With You, Always Evolving.

Validate SeqOne with your own data, expert support, and zero commitment.

Transparent, Flexible Pricing

Pay-per-analysis with no hidden fees or volume constraints.

Personalized Support

Access field specialists, multi-lingual assistance and hands-on guidance.

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